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At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where 'Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.


Vice President Early Development Portfolio Lead 


In Bayer Research & Early Development Oncology, we discover and develop the future of cancer care by focusing on targets that impact tumor-specific vulnerabilities, agnostic to biology or modality, to help us find the medicine that will bring the most value to our patients.


The Early Clinical Development Group is a team of physician-scientists that translates science into patient care focusing on patient centricity, speed and urgency.


The main responsibility of the Early Development Portfolio Leader (EDPL) is to strategically lead the development of the early portfolio for a number of projects and to make sure that program decisions in the assigned areas are in line with the overall oncology portfolio. This includes overseeing the development strategy of individual assets as well as the overall strategy of the assigned portfolio which may include combinations within and outside of the company. The EDPL will be fully responsible as a physician for all medical/clinical aspects for the assigned drug candidates of the portfolio area until PoC.


The Early Development Portfolio Leader is responsible for optimizing the output of development candidates to achieve a seamless development from D1 to Proof of Concept, including target identification efforts. The EDPL serves as the primary clinical contact in due diligence activities when tapping into partnered innovation. The EDPL drives strategic cross-functional and functional initiatives above the individual program level to accelerate drug development and decision making. You will serve as the delegate for the Global Head of Early Clinical Development (ECDO), both internally externally facing, such as e.g. with academic and industry partners, health authorities, key opinion leaders and patient advocacy groups.




The primary responsibilities of this role, Vice President Early Development Portfolio Lead are to:


  • Lead cross-functional and functional activities to accelerate drug development and decision making; drive medical value and differentiation generation in target identification efforts;
  • Set the vision and strategy for the assigned portfolio areas; will prioritize and make strategy recommendations on assigned portfolio area including on strategic external partnerships for new areas such as novel combinations opportunities and new therapeutic modalities;
  • Design a ‘state-of-the-art’ product development strategy for the assigned portfolio area and composing assets based on state-of-the-art science understanding patient, regulatory and commercial needs;
  • Deliver portfolio program milestones in a timely, cost-effective and high-quality fashion from D1 to Proof of Concept. This includes derisking of programs and investments as early as possible;
  • Liaises with Research, Late Development, and Commercial to ensure smooth project transitions through product life-cycle and alignment on the project objectives and deliverables across the portfolio covering multiple MoA across many tumor types;
  • Fully responsible as a physician for all medical/clinical aspects for assigned drug candidates until PoC. Accordingly, responsible for the ongoing benefit/risk assessment of drug candidates and for taking relevant actions and decisions as appropriate, based on the thorough medical/clinical understanding;
  • Ensures timely and transparent and objective communications about program status and issues between IPT and management;
  • Constantly reviews the market environment in order to ensure the program’s strategy is meeting patient, regulatory and commercial needs;
  • Comprehensive knowledge of scientific, development and regulatory landscape to enable state-of-the-art development strategies for all assets;
  • Accountable for driving technical reviews for the programs in the portfolio;
  • Oversee development of the Target Product Profile (TPP) and revisions thereof;
  • Networks with Key Opinion Leaders and maintains effective external scientific advisory boards which is especially important for the new and rapidly developing IO territory;
  • Drives overall R&D assessment and provides medical assessment of in and out-licensing opportunities of development projects;
  • Actively seeks opportunities to represent Bayer in various external forums and panels, such as industry consortia, government-industry panels, professional societies and patient-focused groups;
  • Creates and leads motivated, committed and engaged teams. Models and expects effective team behavior to achieve the project goals.




Your success will be driven by your demonstration of our LIFE values.  More specifically related to this position, Bayer seeks an incumbent who possesses the following:


Required Qualifications:


  • The successful candidate will be a MD or an MD/PhD;
  • Board certification within oncology/hematology or associated subspecialties;
  • Scientific excellence: Demonstrated by a track record of relevant basic and/or translation research documented in peer reviewed publications;
  • Knowledge of the entire R&D process and the key drivers for success as well as strong understanding of the elements of drug development programs;
  • Expertise with cancer and non-cancer cell targeted drugs as well as different modalities including small and large molecules;
  • Relevant global health authority interactions and current knowledge of regulatory review and responses;
  • Exposure to and understanding of commercial considerations in relation to drug development;
  • Excellent communication and leadership skills, coupled with the ability to develop and implement a strategic growth plan;
  • High energy with focus and vision; self-motivated with a high sense of ownership, urgency, proactive and solution-oriented;
  • Strong consensus-building skills and the ability to lead multidisciplinary teams towards sound decision-making;
  • Evidence of ability to lead and manage a team to deliver to time, cost and quality requirements.


Preferred Qualifications:


  • 7+ years of drug development experience with at least 3+ years of expertise in early drug development;
  • Command of a second major European language, especially German.


Relocation may be offered for this position





Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer. 
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below. 

IMPORTANT NOTE for POTENTIAL US CANDIDATES: Bayer expects its colleagues to be fully vaccinated against COVID-19. Bayer defines fully vaccinated in alignment with CDC which is two weeks after completing the two-dose vaccine regimen or two weeks after completing the one-dose regimen. Additionally, Bayer colleagues are also required to comply with state, local and customer requirements.
Location: United States : Massachusetts : Cambridge     
Division: Pharmaceuticals    
Reference Code: 791650     
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